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Scientific Publication

In vivo preliminary investigations of the effects of the benzimidazolen anthelmintic drug flubendazole on rat embryos and fetuses

Abstract

Flubendazole, in a new formulation with high systemic bioavailability, has been proposed as a macrofilaricide against filarial diseases. The embryotoxic activity of a new oral flubendazole formulation was investigated. It did not interfere with rat embryofetal development. This research is part of the Drugs for Neglected Diseases initiative (DNDi)