Report / Evaluation

Evaluation of the Capilia TB Assay for Culture Confirmation of Mycobacterium tuberculosis Infections in Zambia and South Africa

author(s) Godfrey-Faussett, P.. - Beyers, N.. - Muyoyeta, M.. - Ayles, H.. - Mueller, D.H.. - Mwenge, L.. - Schaap, A.. - van Helden, P.D.. - Kruger, C.. - Gey van Pittius, N.C.. - Lawrence, K.. - de Haas, P.E.W.
from UK Foreign, Commonwealth & Development Office (FCDO)
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themes
regions
  • Eastern Africa
  • Sub-Saharan Africa
  • Africa
  • World
  • Southern Africa
citation

Muyoyeta, M.; Mueller, D.H.; van Helden, P.D.; Mwenge, L.; Schaap, A.; Kruger, C.; Gey van Pittius, N.C.; Lawrence, K.; Beyers, N.; Godfrey-Faussett, P.; Ayles, H.; de Haas, P.E.W. Evaluation of the Capilia TB Assay for Culture Confirmation of Mycobacterium tuberculosis Infections in Zambia and South Africa. Journal of Clinical Microbiology (2010) 48 (10) 3773-3775. (DOI: 10.1128/JCM.01688-09)

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Abstract

The performance and cost of the Capilia TB assay were evaluated for use in a resource-limited setting. The sensitivity and specificity were 99.6% and 99.5%, respectively. The incremental costs of the Capilia test were estimated to be $1.46 and $1.84 when the test was added to liquid and solid culture processes, respectively. These findings suggest that the Capilia TB assay represents a rapid, simple, and inexpensive Mycobacterium tuberculosis identification test that can be used in resource-limited settings

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