Scientific Publication

Household-Contact Investigation for Detection of Tuberculosis in Vietnam

author(s) Fox, G.J.. - Nhung, N.V.. - Sy, D.N.. - Hoa, N.L.P.
from UK Foreign, Commonwealth & Development Office (FCDO)
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themes
regions
  • South-Eastern Asia
  • Asia
  • World
  • Northern Europe
  • Europe
citation

Fox GJ, Nhung N V., Sy DN, Hoa NLP, Anh LTN, Anh NT, Hoa NB, Dung NH, Buu TN, Loi NT, Nhung LT, Hung N V., Lieu PT, Cuong NK, Cuong PD, Bestrashniy J, Britton WJ, Marks GB. Household-Contact Investigation for Detection of Tuberculosis in Vietnam. New England Journal of Medicine. 2018;378(3):221–9

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Abstract

Active case finding is a top priority for the global control of tuberculosis, but robust evidence for its effectiveness in high-prevalence settings is lacking. The researchers sought to evaluate the effectiveness of household-contact investigation, as compared with standard, passive measures alone, in Vietnam They performed a cluster-randomized, controlled trial at clinics in 70 districts (local government areas with an average population of approximately 500,000 in urban areas and 100,000 in rural areas) in 8 provinces of Vietnam. This research was supported by the UK Department for International Development’s Operational Research Capacity Building Programme led by the International Union Against TB and Lung Disease (The Union)

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