Scientific Publication

A pyruvate decarboxylase gene from Aspergillus parasiticus

author(s) Archer, D.B.. - Watson, A.J.. - Jeenes, D.J.. - Roberts, I.N.. - Sanchis, V.. - Vinas, I.
from UK Foreign, Commonwealth & Development Office (FCDO)
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FEMS Microbiology Letters (1994) 117 (2) 207-210 (DOI: 10.1111/j.1574-6968.1994.tb06766.x)

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Abstract

A gene encoding a putative pyruvate decarboxylase (EC 4.1.1.1) was isolated from a genomic library of the filamentous fungus Aspergillus parasiticus strain SU-1. The deduced amino acid sequence showed 37% homology to PDC1 from Saccharomyces cerevisiae. Although A. parasiticus has an obligate growth requirement for oxygen, it produced ethanol in shake flask cultures indicating a response to anoxic conditions mediated by pyruvate decarboxylase

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