Scientific Publication
Synthesis and evaluation of analogs of the phenylpyridazinone NPD-001 as potent trypanosomal TbrPDEB1 phosphodiesterase inhibitors and in vitro trypanocidals
Veerman, J.; van den Bergh, T.; Orrling, K.M.; Jansen, C.; Cos, P.; Maes, L.; Chatelain, C.; Ioset, J.R.; Edink, E.E.; Tenor, H.; Seebeck, T.; de Esch, I.; Leurs, R.; Sterk, G.J. Synthesis and evaluation of analogs of the phenylpyridazinone NPD-001 as potent trypanosomal TbrPDEB1 phosphodiesterase inhibitors and in vitro trypanocidals. Bioorganic and Medicinal Chemistry (2016) 24 (7) 1573-1581. (DOI: 10.1016/j.bmc.2016.02.032)